Preliminary insights into the effects of spinal manipulation therapy of different force magnitudes on blood biomarkers of oxidative stress and pro-resolution of inflammation mediators

Table 3 Short-term mean ± (SD) group values of pro-oxidants, antioxidants and resolvin D1 in blood in the studied groups

Blood Biomarkers	Control			400 N			800 N
	Pre- intervention	Immediately after intervention	20 min after intervention	Pre- intervention	Immediately after intervention	20 min after intervention	Pre- intervention	Immediately after intervention	20 min after intervention
TOS	12.40 (4.71)	11.78 (8.34)	9.72 (4.23)	9.43 (3.66)	6.09 (4.42)	6.09 (3.65)	7.92 (4.07)	14.31 (6.54)	13.90 (7.38)
LPO	0.154 (0.02)	0.125 (0.03)	0.141 (0.04)	0.176 (0.04)	0.142 (0.06)	0.128 (0.03)	0.173 (0.04)	0.224 (0.05)	0.216 (0.06)
LOOH	10.00 (0.56)	10.02 (0.61)	9.75 (0.35)	9.57 (0.72)	9.12 (0.85)	9.04 (0.93)	9.45 (0.97)	9.99 (0.82)	10.19 (0.61)
TAC	0.96 (0.08)	0.91 (0.06)	0.92 (0.11)	0.95 (0.09)	0.95 (0.07)	0.95 (0.06)	0.90 (0.13)	0.84 (0.13)	0.92 (0.08)
Total Bilirubin	0.51 (0.13)	0.52 (0.21)	0.51 (0.29)	0.42 (0.19)	0.41 (0.25)	0.42 (0.18)	0.57 (0.30)	0.68 (0.24)	0.58 (0.38)
Resolvin D1	160.18 (36.35)	165.37 (61.72)	185.08 (50.87)	148.54 (37.79)	160.97 (43.04)	156.54 (48.13)	175.85 (33.26)	140.38 (32.47)	138.23 (29.82)

TOS: total oxidant status (µmol H2O2 Equiv/L); LPO (Lipid peroxidation) (TBARS µM): LOOH (Lipid Hydroperoxide) content (µMol/mg protein); TAC: total antioxidant capacity (Trolox mM Equiv/L); Total Bilirubin (mg/dL); Resolvin D1 (Pg/mL)

ISSN: 2045-709X